Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430043 | 0.78 | ALDH1A1 (0.57) | NPC1RAB9ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4050893 | 0.78 | PI4KB (0.41) | BRAFNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL4655958 | 0.77 | MAPT (0.57) | BRAFNPC1RAB9ALMNAMAPT | |
| SCHEMBL4056069 | 0.77 | BRAF (0.56) | BRAFFYN | |
| SCHEMBL4655911 | 0.74 | MAPT (0.62) | BRAFNPC1RAB9ALMNAMAPT | |
| SCHEMBL4059789 | 0.73 | BRAF (0.51) | BRAFFYN | |
| SCHEMBL4058317 | 0.73 | BRAF (0.57) | BRAFMAPTALDH1A1FYN | |
| SCHEMBL4655734 | 0.72 | BRAF (0.75) | BRAFFYN | |
| SCHEMBL4760925 | 0.70 | BRAF (0.81) | BRAFNPC1RAB9ALMNAMAPT | |
| SCHEMBL4657215 | 0.70 | BRAF (0.66) | BRAFNPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |