Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.59 |
| ▸ | PPARD | Q03181 | 16/20 | 0.59 |
| ▸ | PPARA | Q07869 | 14/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055456 | 0.85 | PPARG (0.42) | PPARGPPARDPPARALTB4RLTB4R2 | |
| SCHEMBL4063178 | 0.81 | PPARG (0.75) | PPARGPPARDPPARA | |
| SCHEMBL4055211 | 0.77 | NR1H3 (0.65) | PPARGPPARDPPARA | |
| SCHEMBL4065858 | 0.76 | NR1H3 (0.66) | PPARGPPARDPPARA | |
| SCHEMBL4063594 | 0.75 | NR1H3 (0.65) | PPARGPPARDPPARA | |
| SCHEMBL4064059 | 0.75 | NR1H3 (0.62) | PPARGPPARDPPARA | |
| SCHEMBL5009391 | 0.74 | PPARG (1.00) | PPARGPPARDPPARA | |
| SCHEMBL6616076 | 0.72 | KDM4E (0.51) | PPARGPPARDPPARAKDM4E | |
| SCHEMBL4059391 | 0.72 | PPARG (0.58) | PPARGPPARDPPARALTB4RLTB4R2 | |
| SCHEMBL4063625 | 0.71 | PPARG (0.63) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689389-A4 | INDOLE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-06-17 | — | — | EP | disclosed |
| EP-1689389-A2 | INDOLE COMPOUNDS | National Health Research Institutes (TW) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056522-A2 | INDOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-23 | — | — | WO | disclosed |