Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 15/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 13/20 | 0.62 |
| ▸ | PPARG | P37231 | 11/20 | 0.61 |
| ▸ | PPARD | Q03181 | 10/20 | 0.61 |
| ▸ | PPARA | Q07869 | 9/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065858 | 0.98 | NR1H3 (0.66) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4055211 | 0.98 | NR1H3 (0.65) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4063594 | 0.97 | NR1H3 (0.65) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4063625 | 0.94 | PPARG (0.63) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4059815 | 0.92 | PPARG (0.62) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4064129 | 0.91 | PPARG (0.64) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4052861 | 0.90 | NR1H2 (0.57) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4063178 | 0.85 | PPARG (0.75) | PPARGPPARDPPARA | |
| SCHEMBL2001665 | 0.83 | PPARD (0.72) | NR1H3NR1H2PPARGPPARDPPARA | |
| SCHEMBL4065495 | 0.83 | PPARG (0.60) | NR1H3NR1H2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689389-A4 | INDOLE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-06-17 | — | — | EP | disclosed |
| EP-1689389-A2 | INDOLE COMPOUNDS | National Health Research Institutes (TW) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056522-A2 | INDOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-23 | — | — | WO | disclosed |