Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 6/20 | 0.45 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.45 |
| ▸ | INPP5B | P32019 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054451 | 0.81 | INPPL1 (0.45) | INPPL1INPP5AINPP5BMAPTFBP1 | |
| SCHEMBL12483485 | 0.80 | PTPN1 (0.42) | MAPTKDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL31555373 | 0.77 | INPPL1 (0.57) | INPPL1INPP5AINPP5BMAPTFBP1 | |
| SCHEMBL12484081 | 0.76 | MEN1 (0.36) | MAPTKDM4EALDH1A1POLB | |
| SCHEMBL6736138 | 0.72 | INPPL1 (0.50) | INPPL1INPP5AINPP5BMAPTFBP1 | |
| SCHEMBL8146020 | 0.71 | INPPL1 (0.48) | INPPL1INPP5AINPP5BMAPTFBP1 | |
| SCHEMBL31389012 | 0.70 | INPPL1 (0.52) | INPPL1INPP5AINPP5BMAPTFBP1 | |
| SCHEMBL759513 | 0.69 | MAPT (0.67) | INPPL1INPP5AINPP5BMAPTAKT1 | |
| SCHEMBL1899313 | 0.69 | INPPL1 (0.53) | INPPL1INPP5AINPP5BMAPTAKT1 | |
| SCHEMBL29429257 | 0.69 | MAPT (0.67) | INPPL1INPP5AINPP5BMAPTAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009148192-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2009-12-10 | — | — | WO | claimed |
| WO-2009148192-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2009-12-10 | — | — | WO | disclosed |