Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484081 | 0.85 | MEN1 (0.36) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12483491 | 0.81 | ACHE (0.46) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL4054446 | 0.80 | INPPL1 (0.45) | KDM4EALDH1A1HPGDMAPTUSP2 | |
| SCHEMBL14844977 | 0.79 | PTPN1 (0.46) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL18202141 | 0.78 | PTPN1 (0.48) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL28975051 | 0.78 | MAPK1 (0.47) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL23743764 | 0.71 | KMT2A (0.64) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL10607470 | 0.70 | PTPN1 (0.54) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL14385380 | 0.68 | KDM4E (0.47) | PTPN1ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL742810 | 0.68 | ACHE (0.62) | PTPN1ACHEKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678341-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM Pharma Co., Ltd. (JP) | 2014-01-01 | — | — | EP | claimed |
| WO-2012115286-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-08-30 | — | — | WO | claimed |