Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.64 |
| ▸ | ACP1 | P24666 | 10/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054732 | 1.00 | PTPN1 (0.64) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4053512 | 0.91 | PTPN1 (0.61) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4053511 | 0.91 | PTPN1 (0.61) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4057079 | 0.90 | PTPN1 (0.76) | PTPN1ACP1PTPN2AURKA | |
| SCHEMBL4057081 | 0.90 | PTPN1 (0.76) | PTPN1ACP1PTPN2AURKA | |
| SCHEMBL4051012 | 0.88 | PTPN1 (0.83) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4051017 | 0.88 | PTPN1 (0.83) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4051497 | 0.88 | PTPN1 (0.68) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4051498 | 0.88 | PTPN1 (0.68) | PTPN1ACP1PTPN2AURKAITGB3 | |
| SCHEMBL4225045 | 0.82 | PTPN1 (0.73) | PTPN1ACP1PTPN2AURKAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |