Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038561 | 0.94 | PLAU (0.40) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL2448020 | 0.89 | HSD17B10 (0.42) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL11239759 | 0.87 | HPGD (0.44) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL8408841 | 0.83 | MAPT (0.42) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL8408517 | 0.82 | HPGD (0.46) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL2376058 | 0.82 | MAPT (0.54) | HPGDCYP3A4PLAUMAPTMAPK1 | |
| SCHEMBL11705523 | 0.82 | PLAU (0.43) | HPGDCYP3A4PLAUMAPTMAPK1 | |
| SCHEMBL8406353 | 0.82 | PLAU (0.40) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL8405926 | 0.82 | PLAU (0.40) | HPGDHSD17B10CYP3A4CRHBPCRHR2 | |
| SCHEMBL8407169 | 0.81 | HPGD (0.40) | HPGDHSD17B10CYP3A4CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620093-B1 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620093-B1 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620093-A4 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-7208450-B2 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | BAYER CROPSCIENCE AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208450-B2 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | BAYER CROPSCIENCE AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208450-B2 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | BAYER CROPSCIENCE AG (DE) | 2007-04-24 | — | — | US | disclosed |
| EP-1620093-A2 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050171356-A1 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | FMC CORPORATION | 2005-08-04 | — | — | US | disclosed |
| WO-2004099105-A2 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171356-A1 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | DDT, PDHX, CYP4X1 | HPGD 2807/4885HSD17B10 1488/4885CYP3A4 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.