Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.36 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178305 | 0.78 | CYP8B1 (0.44) | KCNH2CYP8B1 | |
| SCHEMBL3179377 | 0.71 | CYP8B1 (0.46) | KCNH2CYP8B1 | |
| SCHEMBL1224385 | 0.71 | CYP8B1 (0.46) | KCNH2CYP8B1 | |
| SCHEMBL3665601 | 0.71 | CYP8B1 (0.46) | KCNH2CYP8B1 | |
| SCHEMBL4066839 | 0.71 | CYP8B1 (0.46) | KCNH2CYP8B1 | |
| SCHEMBL1222834 | 0.71 | CYP2C19 (0.46) | KCNH2CYP8B1 | |
| SCHEMBL10078632 | 0.70 | HTR2C (0.45) | KCNH2CYP8B1 | |
| SCHEMBL1222886 | 0.70 | CYP8B1 (0.41) | KCNH2CYP8B1 | |
| SCHEMBL3636416 | 0.69 | CYP2C19 (0.54) | KCNH2CYP8B1 | |
| SCHEMBL3634872 | 0.69 | CYP2C19 (0.54) | KCNH2CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773343-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-05-13 | — | — | EP | disclosed |
| EP-1773343-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006017326-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |