Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL857349 | 0.83 | EGFR (0.32) | EGFR | |
| SCHEMBL3934464 | 0.71 | EGFR (0.38) | EGFR | |
| SCHEMBL275756 | 0.70 | MAPT (0.41) | — | |
| SCHEMBL3941587 | 0.68 | EGFR (0.34) | EGFR | |
| SCHEMBL3933123 | 0.67 | — | — | |
| SCHEMBL158554 | 0.67 | CLK1 (0.33) | — | |
| SCHEMBL855569 | 0.67 | EGFR (0.32) | EGFR | |
| SCHEMBL80566 | 0.67 | EGFR (0.47) | EGFR | |
| SCHEMBL16717215 | 0.64 | CLK1 (0.35) | — | |
| SCHEMBL137377 | 0.64 | EGFR (0.60) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | claimed |
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| EP-2017264-A1 | Substituted phenyl propargyl compounds, method for their manufacture and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | EP | disclosed |