SCHEMBL3934464

SCHEMBL3934464

[c]1nccc2cncnc12

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 9/20 0.38
MKNK2 Q9HBH9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055162 0.71 EGFR (0.38) EGFR
SCHEMBL3935658 0.70 EGFR (0.35) EGFR
SCHEMBL159538 0.70 PRKCZ (0.33)
SCHEMBL276596 0.70 KDM4E (0.41)
SCHEMBL27674458 0.68 PRKCZ (0.32)
SCHEMBL27202903 0.68 HTT (0.32)
SCHEMBL158554 0.67 CLK1 (0.33)
SCHEMBL3937240 0.67
SCHEMBL8311252 0.67 EGFR (0.38) EGFR
SCHEMBL20483 0.67 EGFR (0.47) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009010156-A2 SUBSTITUTED PHENYLPROPOARGYL COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF SAME AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2009-01-22 WO disclosed
EP-2017264-A1 Substituted phenyl propargyl compounds, method for their manufacture and their use as herbicides and plant growth regulators BAYER CROPSCIENCE AG (DE) 2009-01-21 EP disclosed