Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750905 | 0.85 | ESR1 (0.34) | LMNAMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9389956 | 0.82 | ALDH1A1 (0.42) | LMNAMAPK1SMN1; SMN2NPC1CASP3 | |
| SCHEMBL8749915 | 0.78 | MAPK1 (0.35) | LMNAMAPK1SMN1; SMN2NPC1CASP3 | |
| SCHEMBL3907799 | 0.77 | ALDH1A1 (0.48) | LMNAMAPK1SMN1; SMN2NPC1CASP3 | |
| SCHEMBL30359261 | 0.77 | ALDH1A1 (0.48) | LMNAMAPK1SMN1; SMN2NPC1CASP3 | |
| SCHEMBL26632605 | 0.76 | ALDH1A1 (0.47) | LMNAMAPK1SMN1; SMN2NPC1CASP3 | |
| SCHEMBL11314863 | 0.76 | ESR1 (0.35) | LMNAMAPK1SMN1; SMN2ATMALDH1A1 | |
| SCHEMBL11747030 | 0.74 | ALDH1A1 (0.36) | LMNASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL31438668 | 0.74 | ALDH1A1 (0.43) | LMNAATMALDH1A1TSHRTDP1 | |
| SCHEMBL1159985 | 0.74 | ALDH1A1 (0.43) | LMNAATMALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120210-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-10-01 | — | — | WO | disclosed |