Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDKN1A | P38936 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060366 | 0.98 | CDKN1A (0.52) | CDKN1AKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4060204 | 0.89 | KMT2A (0.48) | KMT2APOLB | |
| SCHEMBL4057593 | 0.88 | KMT2A (0.53) | KMT2A | |
| SCHEMBL4061853 | 0.87 | KMT2A (0.50) | KMT2APOLB | |
| SCHEMBL4060486 | 0.86 | ALDH1A1 (0.56) | CDKN1AKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4058619 | 0.86 | KMT2A (0.49) | KMT2APOLB | |
| SCHEMBL4055973 | 0.84 | CDKN1A (0.52) | CDKN1AKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL4065547 | 0.83 | KMT2A (0.46) | KMT2A | |
| SCHEMBL4057460 | 0.82 | CDKN1A (0.52) | CDKN1AKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4057465 | 0.82 | KMT2A (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828199-B1 | THIENO-PYRIDINE DERIVATIVES AS GABA-B ALLOSTERIC ENHANCERS | HOFFMANN LA ROCHE (CH) | 2009-05-06 | — | — | EP | claimed |