SCHEMBL40557

SCHEMBL40557

COc1ccc(C(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.61
ACP3 P15309 1/20 0.60
CA4 P22748 1/20 0.59
NR3C1 P04150 1/20 0.57
PGR P06401 1/20 0.57
NR3C2 P08235 1/20 0.57
AR P10275 1/20 0.57
LTA4H P09960 2/20 0.56
ALDH1A1 P00352 4/20 0.55
PBRM1 Q86U86 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
TRPA1 O75762 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13295535 1.00 SLC2A1 (0.61) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL14205685 1.00 SLC2A1 (0.61) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL13295540 1.00 SLC2A1 (0.61) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL34971 1.00 SLC2A1 (0.61) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL13295537 1.00 SLC2A1 (0.61) SLC2A1ACP3CA4NR3C1PGR
Hydrochloric Acid SCHEMBL28430528 0.98 SLC2A1 (0.59) SLC2A1ACP3CA4NR3C1PGR
Hydrochloric Acid SCHEMBL10530921 0.98 SLC2A1 (0.59) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL28801049 0.92 SLC2A1 (0.53) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL16203305 0.92 ACHE (0.60) SLC2A1ACP3CA4NR3C1PGR
SCHEMBL16859725 0.90 SLC2A1 (0.71) SLC2A1ACP3CA4NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13032 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118512928-A Forward osmosis membrane based on TFB-33-DMTH and preparation method and application thereof 济南大学 2024-08-20 CN claimed
US-12043642-B2 Process for the purification of oligonucleotides GENENTECH, INC. (US) 2024-07-23 US claimed
EP-4396193-A1 FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS Hongene Biotech Corporation (US) 2024-07-10 EP claimed
US-12030907-B2 Modified nucleoside phosphoramidites Janssen Biopharma, Inc. (US) 2024-07-09 US claimed
WO-2024139896-A1 SUGAR RING MODIFIED NUCLEOSIDE PHOSPHORAMIDITE MONOMER, PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院深圳先进技术研究院 2024-07-04 WO claimed
CN-118271378-A Sugar ring modified nucleoside phosphoramidite monomer and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-07-02 CN claimed
WO-2024135721-A1 METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME 田辺三菱製薬株式会社 2024-06-27 WO claimed
WO-2024137756-A1 COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION (US) 2024-06-27 WO claimed
WO-2024135609-A1 LINKER FOR NUCLEIC ACID SYNTHESIS, CARRIER, AND METHODS FOR PRODUCING SAME シンクレスト株式会社 2024-06-27 WO claimed
CN-115038790-B Synthesis of 3' -RNA oligonucleotides 阿尔尼拉姆医药品有限公司 2024-06-21 CN claimed
US-4452807-A CENTRAL NERVOUS SYSTEM DISORDERS HOFFMANN-LA ROCHE INC. (US) 1984-06-05 US claimed
US-4407750-A Unsymmetrical azetidinone aldehyde disulfides and process ELI LILLY AND COMPANY (US) 1983-10-04 US claimed
US-4394313-A Symmetrical azetidinone aldehyde disulfides and process ELI LILLY AND COMPANY (US) 1983-07-19 US claimed
EP-0082668-A1 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections BEECHAM GROUP PLC (GB) 1983-06-29 EP claimed
US-4335240-A Process for cyclization ELI LILLY AND COMPANY (US) 1982-06-15 US claimed
US-4310662-A Nucleosidic phosphorylating agent and methods GENENTECH, INC. (US) 1982-01-12 US claimed
US-4302391-A Unsymmetrical azetidinone aldehyde disulfides and process ELI LILLY AND COMPANY (US) 1981-11-24 US claimed
US-4293495-A Symmetrical azetidinone aldehyde disulfides and process ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
US-4293493-A Azetidinone alcohol disulfides and process for cyclization ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
EP-0002322-A2 Improved Triester process for the synthesis of oligonucleotides GENENTECH, INC. (US) 1979-06-13 EP claimed