SCHEMBL4055729

SCHEMBL4055729

COc1ccc(CCc2cnc3c(N)nc4cc(C(=O)O)ccc4c3c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008731 0.91 TLR7 (0.63) TLR7
SCHEMBL1006645 0.85 TLR7 (0.61) TLR7
SCHEMBL16735821 0.84 TLR7 (0.50) TLR7
SCHEMBL1057766 0.84 TLR7 (0.58) TLR7
SCHEMBL1008053 0.84 TLR7 (0.62) TLR7
SCHEMBL1007823 0.84 TLR7 (0.54) TLR7
SCHEMBL2364496 0.84 TLR7 (0.53) TLR7
SCHEMBL1007853 0.82 TLR7 (0.55) TLR7
SCHEMBL12723160 0.81 TLR7 (0.81) TLR7
SCHEMBL1704392 0.80 TLR7 (0.66) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009111337-A1 COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS IRM LLC (BM) 2009-09-11 WO disclosed