Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22806647 | 0.82 | LMNA (0.43) | MAPTHTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL11845620 | 0.78 | SMN1; SMN2 (0.56) | ALDH1A1MAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL11846407 | 0.78 | LMNA (0.41) | AURKANTRK1LMNARAB9A | |
| SCHEMBL11836087 | 0.77 | TP53 (0.47) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL982864 | 0.75 | LMNA (0.55) | ALDH1A1MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL13557323 | 0.74 | MEN1 (0.47) | ALDH1A1HTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL11842504 | 0.74 | LMNA (0.40) | MAPTSMN1; SMN2AURKANTRK1LMNA | |
| SCHEMBL9085841 | 0.73 | GAA (0.67) | ALDH1A1MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL13924144 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1KDM4EHTTSMN1; SMN2GAA | |
| SCHEMBL5209865 | 0.73 | ESR1 (0.53) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |