Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 16/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703721 | 0.87 | SSTR5 (0.43) | SSTR5KCNH2SSTR3SLC6A2SLC6A4 | |
| SCHEMBL4702314 | 0.85 | TACR1 (0.41) | SSTR5KCNH2TACR1SLC6A2SLC6A4 | |
| SCHEMBL4700562 | 0.85 | SSTR5 (0.41) | SSTR5KCNH2SSTR3SLC6A2SLC6A4 | |
| SCHEMBL4702988 | 0.84 | SSTR5 (0.40) | SSTR5KCNH2SSTR3SLC6A2SLC6A4 | |
| SCHEMBL4594815 | 0.83 | NPC1 (0.40) | SSTR5KCNH2SSTR3TACR1 | |
| SCHEMBL3979077 | 0.78 | SSTR5 (0.40) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3979380 | 0.78 | SSTR5 (0.41) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3974394 | 0.78 | SSTR5 (0.40) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3995784 | 0.78 | SSTR5 (0.45) | SSTR5KCNH2SSTR3SLC6A2SLC6A4 | |
| SCHEMBL3978569 | 0.77 | SSTR5 (0.45) | SSTR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |