Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 18/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700562 | 0.91 | SSTR5 (0.41) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3971951 | 0.85 | SSTR5 (0.40) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3974394 | 0.85 | SSTR5 (0.40) | SSTR5KCNH2SSTR3HTR2A | |
| SCHEMBL3975340 | 0.83 | SSTR5 (0.38) | SSTR5KCNH2SSTR3HTR2A | |
| SCHEMBL4593376 | 0.82 | SSTR5 (0.36) | SSTR5KCNH2SSTR3 | |
| SCHEMBL4703721 | 0.79 | SSTR5 (0.43) | SSTR5KCNH2SSTR3 | |
| SCHEMBL4704418 | 0.79 | SLC6A2 (0.41) | SSTR5KCNH2HTR2A | |
| SCHEMBL3979380 | 0.79 | SSTR5 (0.41) | SSTR5KCNH2SSTR3HTR2A | |
| SCHEMBL4591930 | 0.78 | POLB (0.42) | SSTR5KCNH2HTR2A | |
| SCHEMBL4055974 | 0.78 | SSTR5 (0.41) | SSTR5KCNH2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054385-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-05-06 | — | — | EP | claimed |
| WO-2008019967-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-21 | — | — | WO | claimed |
| EP-2054385-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008019967-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-21 | — | — | WO | disclosed |