Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056197 | 1.00 | MEN1 (0.60) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL2595128 | 0.88 | MEN1 (0.71) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL2595132 | 0.88 | MEN1 (0.71) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL14876942 | 0.88 | MEN1 (0.71) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL2587984 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL2587982 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL2586777 | 0.80 | KMT2A (0.53) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL4056949 | 0.80 | MEN1 (0.53) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL4056952 | 0.80 | MEN1 (0.53) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL2586772 | 0.80 | KMT2A (0.53) | MEN1KMT2AALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |