Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.49 |
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056274 | 0.92 | HTR3A (0.46) | CNR1CNR2HTR3ARETGRM4 | |
| SCHEMBL13691217 | 0.91 | CNR1 (0.58) | CNR1CNR2HTR3ARET | |
| SCHEMBL4052555 | 0.90 | CNR1 (0.47) | CNR1CNR2HTR3AGRM4NR3C1 | |
| SCHEMBL13690937 | 0.88 | CNR1 (0.61) | CNR1CNR2HTR3ARETGRM4 | |
| SCHEMBL4049658 | 0.86 | HTR3A (0.46) | CNR1CNR2HTR3ARETGRM4 | |
| SCHEMBL13690846 | 0.86 | HTR3A (0.46) | CNR1CNR2HTR3ARETGRM4 | |
| SCHEMBL4050831 | 0.86 | CNR1 (0.64) | CNR1CNR2HTR3A | |
| SCHEMBL4050996 | 0.86 | CNR1 (0.54) | CNR1CNR2HTR3ARETGRM4 | |
| SCHEMBL4059061 | 0.85 | CNR1 (0.47) | CNR1CNR2HTR3ARETGRM4 | |
| SCHEMBL13690935 | 0.85 | CNR1 (0.47) | CNR1CNR2HTR3ARETGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |