SCHEMBL4057

SCHEMBL4057

Brc1[c]ccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249565 0.57
SCHEMBL3708515 0.53
SCHEMBL3711452 0.48
SCHEMBL3072076 0.44
SCHEMBL1156793 0.43 GPR35 (0.41)
SCHEMBL1995763 0.43
SCHEMBL1173857 0.42
SCHEMBL25275597 0.38
Calcium Bromide SCHEMBL27725349 0.38
Calcium Bromide SCHEMBL28133914 0.38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
EP-4223753-A1 AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2023-08-09 EP claimed
CN-116234550-A Aromatic formyl substituted tricyclic compound and preparation method and application thereof 劲方医药科技(上海)有限公司 2023-06-06 CN claimed
US-20230151025-A1 SUBSTITUTED THIAZOLOPYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AG (DE) 2023-05-18 US claimed
WO-2023036707-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2023-03-16 WO claimed
WO-2023036706-A1 SUBSTITUTED THIAZOLOPYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2023-03-16 WO claimed
EP-4132938-A1 SUBSTITUTED THIAZOLOPYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-02-15 EP claimed
CN-115698021-A Substituted thiazolopyridines, salts thereof and their use as herbicidal active substances 拜耳公司 2023-02-03 CN claimed
CN-114213353-A Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2022-03-22 CN claimed
US-9422276-B2 Use of aryl and hetaryl carboxamides as endoparasiticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-23 US claimed
CN-102985417-B Piperidin-4-yl azetidine derivatives as JAK1 inhibitors INCYTE CORP 2015-01-28 CN claimed
CN-104203223-A Use of aryl and hetaryl carboxamides as endoparasiticides BAYER IP GMBH 2014-12-10 CN claimed
US-20140323736-A1 USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-10-30 US claimed
EP-2782565-A1 USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES Bayer Intellectual Property GmbH (DE) 2014-10-01 EP claimed
WO-2013076230-A1 USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-30 WO claimed
WO-2009077497-A2 AZOLYL METHYL OXIRANES, THE USE THEREOF, AND AGENTS CONTAINING THEM BASF SE (DE) 2009-06-25 WO claimed
EP-0228887-B1 DIOXANE HEXENOIC ACIDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-24 EP claimed
US-4585472-A PRE- AND POSTEMERGENCE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US claimed
EP-0102542-A2 1,2,4,6-Thiatriazin-1,1-dioxide ethers, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-03-14 EP claimed