SCHEMBL4057013

SCHEMBL4057013

On1nnc2c1CC=CC2

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1720810 0.98
SCHEMBL9858158 0.65 PKM (0.31)
SCHEMBL8189032 0.63
SCHEMBL12251821 0.45 PIK3CD (0.34) POLB
SCHEMBL12629755 0.43
SCHEMBL10638723 0.41
SCHEMBL52489 0.39
SCHEMBL11809662 0.39
SCHEMBL11376825 0.39 TRIM24 (0.31)
SCHEMBL2230333 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009106980-A2 INDAZOLE DERIVATIVES PFIZER INC. (US) 2009-09-03 WO disclosed
EP-1456659-B1 IMMOBILIZATION OF BINDING AGENTS GE HEALTHCARE BIO SCIENCES AB (SE) 2008-03-12 EP disclosed
US-20060223113-A1 Immobilization of binding agents BIACORE AB (SE) 2006-10-05 US disclosed