Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298890 | 0.85 | MAPT (0.48) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL4054862 | 0.79 | KDM4E (0.55) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL29684351 | 0.76 | KCNK3 (0.74) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL4055861 | 0.75 | MAP4K4 (0.54) | SMN1; SMN2KMT2AKCNK3KCNK9HPGD | |
| SCHEMBL13655257 | 0.75 | MAPT (0.58) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL4061445 | 0.74 | HPGD (0.54) | SMN1; SMN2LMNAKCNK3KCNK9HPGD | |
| SCHEMBL4243575 | 0.73 | TRPV1 (0.53) | — | |
| SCHEMBL23011772 | 0.73 | KCNK3 (0.82) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL13874759 | 0.72 | MAPT (1.00) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL29684417 | 0.71 | MAPT (0.57) | MAPTSMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |