Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.53 |
| ▸ | PLK1 | P53350 | 6/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059876 | 0.88 | PLK1 (0.48) | TRPV1PLK1NR1H4 | |
| SCHEMBL4066870 | 0.87 | PLK1 (0.49) | TRPV1PLK1PLK3 | |
| SCHEMBL4236780 | 0.81 | PLK1 (0.54) | TRPV1PLK1PLK3 | |
| SCHEMBL4057257 | 0.78 | TRPV1 (0.55) | TRPV1PLK1NR1H4 | |
| SCHEMBL4060205 | 0.77 | MAPT (0.50) | — | |
| Hydrochloric Acid SCHEMBL4303740 | 0.77 | TRPV1 (0.54) | TRPV1PLK1NR1H4 | |
| SCHEMBL13655379 | 0.77 | TRPV1 (0.56) | TRPV1PLK1PLK3 | |
| SCHEMBL4054862 | 0.75 | KDM4E (0.55) | — | |
| SCHEMBL4057336 | 0.73 | MAPT (0.55) | — | |
| SCHEMBL22556340 | 0.73 | TRPV1 (0.84) | TRPV1PLK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |