Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.82 |
| ▸ | MMP13 | P45452 | 3/20 | 0.78 |
| ▸ | MMP3 | P08254 | 2/20 | 0.78 |
| ▸ | GSK3B | P49841 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.64 |
| ▸ | CTSD | P07339 | 2/20 | 0.64 |
| ▸ | NAT1 | P18440 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SI | P14410 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057345 | 1.00 | HPGD (0.82) | HPGDMMP13MMP3GSK3BPOLB | |
| SCHEMBL7969672 | 0.94 | HPGD (0.82) | HPGDMMP13MMP3GSK3BPOLB | |
| SCHEMBL7969676 | 0.94 | HPGD (0.82) | HPGDMMP13MMP3GSK3BPOLB | |
| SCHEMBL1300347 | 0.90 | HPGD (1.00) | HPGDPOLBPTPN1MAOAMAOB | |
| SCHEMBL1300345 | 0.90 | HPGD (1.00) | HPGDPOLBPTPN1MAOAMAOB | |
| SCHEMBL6866778 | 0.90 | HPGD (1.00) | HPGDPOLBPTPN1MAOAMAOB | |
| SCHEMBL4061047 | 0.89 | NAT1 (0.70) | HPGDMMP13MMP3POLBMEN1 | |
| SCHEMBL4061045 | 0.89 | NAT1 (0.70) | HPGDMMP13MMP3POLBMEN1 | |
| SCHEMBL12892045 | 0.88 | MMP13 (1.00) | HPGDMMP13MMP3POLBMEN1 | |
| SCHEMBL1248973 | 0.88 | MMP13 (1.00) | HPGDMMP13MMP3POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |