Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047130 | 0.80 | PDE4B (0.52) | MAPTKDM4EGAAALDH1A1PKM | |
| SCHEMBL6777873 | 0.79 | CA12 (0.45) | KMT2AMEN1MAPTKDM4EATM | |
| SCHEMBL4050780 | 0.78 | MAPT (0.61) | KMT2AMEN1MAPTKDM4EGAA | |
| SCHEMBL4904367 | 0.78 | KMT2A (0.48) | KMT2AMEN1MAPK10MAPTKDM4E | |
| SCHEMBL30629472 | 0.78 | KMT2A (0.52) | KMT2AMEN1MAPK10MAPTKDM4E | |
| SCHEMBL4906865 | 0.78 | KMT2A (0.54) | KMT2AMEN1MAPK10MAPTKDM4E | |
| SCHEMBL30629554 | 0.76 | KMT2A (0.50) | KMT2AMEN1MAPK10MAPTKDM4E | |
| SCHEMBL11691158 | 0.75 | KMT2A (0.47) | KMT2AMEN1MAPK10MAPTKDM4E | |
| SCHEMBL2911629 | 0.74 | KMT2A (0.48) | KMT2AMEN1MAPK10MAPTKDM4E | |
| SCHEMBL2718914 | 0.73 | KMT2A (0.50) | KMT2AMEN1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035434-A1 | QUINOLINE DERIVATIVES, THEIR PREPARATION, THEIR USE, AND MEDICAMENTS COMPRISING THEM | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |
| US-20080056987-A1 | Quinoline derivatives, their preparation, their use, and medicaments comprising them | BAYER SCHERING PHARMA AG (DE) | 2008-03-06 | — | — | US | disclosed |
| WO-2007147578-A1 | QUINOLINE DERIVATIVES, THEIR PREPARATION, THEIR USE, AND MEDICAMENTS COMPRISING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080056987-A1 | Quinoline derivatives, their preparation, their use, and medicaments comprising them | RECQL, NQO2, XDH | KMT2A 1600/4885MEN1 634/4885MAPK10 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.