Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.38 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690583 | 1.00 | CNR1 (0.52) | CNR1CNR2GUCY1A1GUCY1B1KDM4C | |
| SCHEMBL4055448 | 0.93 | CNR1 (0.52) | CNR1CNR2GUCY1A1GUCY1B1KDM4C | |
| SCHEMBL4056281 | 0.92 | ROCK1 (0.43) | CNR1CNR2ROCK1HTR4 | |
| SCHEMBL4049662 | 0.90 | CNR1 (0.59) | CNR1CNR2GUCY1A1GUCY1B1KDM4C | |
| SCHEMBL4052498 | 0.89 | CNR1 (0.49) | CNR1CNR2GUCY1A1GUCY1B1KDM4C | |
| SCHEMBL13691275 | 0.89 | CNR1 (0.49) | CNR1CNR2GUCY1A1GUCY1B1KDM4C | |
| SCHEMBL4054945 | 0.88 | CNR1 (0.67) | CNR1CNR2CFDHTR4 | |
| SCHEMBL4051743 | 0.88 | CNR1 (0.67) | CNR1CNR2CFDHTR4 | |
| SCHEMBL13691313 | 0.88 | CNR1 (0.67) | CNR1CNR2CFDHTR4 | |
| SCHEMBL13691265 | 0.87 | CNR1 (0.50) | CNR1CNR2GUCY1A1GUCY1B1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |