⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982239 | 0.61 | — | — | |
| SCHEMBL1235645 | 0.58 | — | — | |
| SCHEMBL9252020 | 0.57 | — | — | |
| SCHEMBL6434247 | 0.52 | — | — | |
| SCHEMBL17468172 | 0.49 | — | — | |
| SCHEMBL2059781 | 0.47 | ALDH1A1 (0.50) | — | |
| SCHEMBL363405 | 0.47 | — | — | |
| SCHEMBL10596214 | 0.45 | MEN1 (0.35) | — | |
| SCHEMBL10596219 | 0.45 | MEN1 (0.35) | — | |
| SCHEMBL196799 | 0.45 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204377-A1 | AMINOPYRIDYLOXYPYRAZOLE COMPOUNDS | Eli Lilly and Company (US) | 2017-08-16 | — | — | EP | claimed |
| WO-2016057278-A1 | AMINOPYRIDYLOXYPYRAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2016-04-14 | — | — | WO | claimed |
| EP-3204377-A1 | AMINOPYRIDYLOXYPYRAZOLE COMPOUNDS | Eli Lilly and Company (US) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016057278-A1 | AMINOPYRIDYLOXYPYRAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2016-04-14 | — | — | WO | disclosed |
| WO-2009122148-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-08 | — | — | WO | disclosed |