Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | FPR1 | P21462 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904726 | 0.91 | ALDH1A1 (0.74) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL13904700 | 0.85 | ALDH1A1 (0.67) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL4057641 | 0.80 | MAPT (0.66) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL13904767 | 0.76 | ALDH1A1 (0.78) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL13904566 | 0.75 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL5267169 | 0.75 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL13904577 | 0.72 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL11558235 | 0.70 | ALDH1A1 (0.81) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL10619815 | 0.70 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTMAPK1MAPT | |
| SCHEMBL25943638 | 0.70 | KDM4E (0.58) | ALDH1A1LMNAHTTMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026657-A1 | FLAVONOID PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009026657-A1 | FLAVONOID PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |