Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570394 | 0.88 | EPHX2 (0.58) | EPHX2RAB9ANPC1HSPA9 | |
| SCHEMBL2570538 | 0.84 | MEN1 (0.45) | EPHX2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL13654290 | 0.82 | EPHX2 (0.52) | EPHX2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL1595003 | 0.82 | EPHX2 (0.55) | EPHX2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL4069869 | 0.82 | MAPT (0.44) | EPHX2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL2565355 | 0.80 | EPHX2 (0.48) | EPHX2RAB9ANPC1MAPTKMT2A | |
| SCHEMBL2569997 | 0.80 | MAPT (0.48) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6673563 | 0.78 | MTTP (0.47) | KMT2A | |
| SCHEMBL2571142 | 0.76 | EPHX2 (0.54) | EPHX2RAB9ANPC1MAPTKMT2A | |
| SCHEMBL2568013 | 0.75 | EPHX2 (0.52) | EPHX2RAB9ANPC1MAPTHSPA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853582-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |