Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 14/20 | 0.47 |
| ▸ | APOB | P04114 | 4/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.43 |
| ▸ | MICA | Q29983 | 1/20 | 0.43 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673495 | 0.86 | MTTP (0.49) | MTTPAPOBS1PR1S1PR3 | |
| SCHEMBL6673562 | 0.85 | MTTP (0.47) | MTTPAPOBS1PR1S1PR3KLRK1 | |
| SCHEMBL6672977 | 0.83 | P2RY14 (0.43) | MTTPAPOBS1PR1S1PR3 | |
| SCHEMBL6675701 | 0.82 | MTTP (0.46) | MTTPAPOB | |
| SCHEMBL6674378 | 0.80 | MTTP (0.44) | MTTPAPOB | |
| SCHEMBL6673930 | 0.80 | MTTP (0.51) | MTTPAPOB | |
| SCHEMBL6676843 | 0.79 | MTTP (0.48) | MTTPAPOBALDH1A1HPGDKMT2A | |
| SCHEMBL4057959 | 0.78 | EPHX2 (0.51) | KMT2A | |
| SCHEMBL6678710 | 0.78 | ALDH1A1 (0.48) | MTTPAPOBALDH1A1HPGDKMT2A | |
| SCHEMBL7039285 | 0.78 | MTTP (0.51) | MTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465613-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057205-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-07-17 | — | — | WO | disclosed |
| WO-2003004020-A1 | HETEROARYL CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-01-16 | — | — | WO | disclosed |