Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.65 |
| ▸ | MAX | P61244 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058214 | 1.00 | MYC (0.65) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4058211 | 1.00 | MYC (0.65) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4057966 | 1.00 | MYC (0.65) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4056062 | 0.91 | MYC (0.81) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4054059 | 0.91 | MYC (0.65) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4056061 | 0.91 | MYC (0.81) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4054061 | 0.91 | MYC (0.65) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4049180 | 0.89 | MYC (0.64) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4049181 | 0.89 | MYC (0.64) | MYCMAXHPGDALDH1A1MAPT | |
| SCHEMBL4053862 | 0.89 | ALOX5 (0.65) | MYCMAXHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |