Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4066832 | 0.84 | ANPEP (0.31) | — | |
| SCHEMBL7191914 | 0.78 | — | — | |
| SCHEMBL5345831 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL4329729 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL15329501 | 0.73 | PBRM1 (0.35) | — | |
| Bromide SCHEMBL8160255 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3808738 | 0.72 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3692671 | 0.71 | ANPEP (0.32) | — | |
| Hydrochloric Acid SCHEMBL5951513 | 0.70 | PBRM1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4063434 | 0.70 | ANPEP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205363-B2 | Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene | EXXON MOBIL CHEMICAL PATENTS INC. (US) | 2007-04-17 | — | — | US | claimed |
| US-6846770-B2 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-01-25 | — | — | US | claimed |
| WO-2005003184-A1 | POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-01-13 | — | — | WO | claimed |
| US-20040254316-A1 | Polymerization processes using antistatic agents | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-16 | — | — | US | claimed |
| US-6667272-B2 | Metallocene, an activator and a fluorided support; use as alpha-olefin polymerization catalysts, polypropylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-12-23 | — | — | US | claimed |
| US-6664348-B2 | Metallocene catalyst such as dimethylsilandiylbis(2-ethyl-4-phenyl-1-indenyl)zirconium dimethyl for polymerization of propylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-12-16 | — | — | US | claimed |
| US-6524988-B2 | Metallocene, an activator and a fluorided support; polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-02-25 | — | — | US | claimed |
| US-20020169261-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-11-14 | — | — | US | claimed |
| US-20020160914-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-10-31 | — | — | US | claimed |
| EP-1109839-A1 | HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS | ExxonMobil Chemical Patents Inc. (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000012565-A1 | HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS | EXXON CHEMICAL PATENTS INC. (US) | 2000-03-09 | — | — | WO | claimed |
| EP-2045304-A2 | Polypropylene-Based Adhesive Compositions | ExxonMobil Chemical Patents Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1311593-B1 | POLYPROPYLENE FILMS | EXXONMOBIL CHEM PATENTS INC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-7205363-B2 | Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene | EXXON MOBIL CHEMICAL PATENTS INC. (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1315858-B1 | POLYPROPYLENE FIBERS AND FABRICS | EXXONMOBIL CHEM PATENTS INC (US) | 2007-02-07 | — | — | EP | disclosed |
| US-20010044506-A1 | Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-11-22 | — | — | US | disclosed |
| US-20010039314-A1 | Propylene polymers for films | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-11-08 | — | — | US | disclosed |
| WO-2001046277-A2 | POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001036499-A1 | PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001032757-A1 | FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-05-10 | — | — | WO | disclosed |