Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29253910 | 0.69 | KDM4E (0.45) | ALDH1A1CA2RAB9ASLC6A3KMT2A | |
| SCHEMBL31650964 | 0.69 | ALDH1A1 (0.56) | ALDH1A1CA2RAB9ASLC6A3KMT2A | |
| SCHEMBL28452557 | 0.67 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3KMT2A | |
| SCHEMBL983728 | 0.67 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3KMT2A | |
| SCHEMBL15692442 | 0.67 | ALDH1A1 (0.43) | ALDH1A1CA2RAB9ASLC6A3KMT2A | |
| Biphenyl SCHEMBL29552487 | 0.64 | ALDH1A1 (0.90) | ALDH1A1CA2RAB9ALMNAMAPT | |
| Biphenyl SCHEMBL38656493 | 0.64 | ALDH1A1 (0.90) | ALDH1A1CA2RAB9ALMNAMAPT | |
| SCHEMBL14064807 | 0.63 | ALDH1A1 (0.50) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL24624826 | 0.61 | ALDH1A1 (0.47) | ALDH1A1CA2RAB9ASLC6A3KMT2A | |
| SCHEMBL1199046 | 0.60 | EPHX1 (0.52) | KMT2AMEN1POLBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207877-B1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | BRIGHAM & WOMENS HOSPITAL (US) | 2009-10-21 | — | — | EP | disclosed |
| US-6916843-B1 | Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1207877-A4 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | BRIGHAM & WOMENS HOSPITAL (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1207877-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010438-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2001-02-15 | — | — | WO | disclosed |