Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067480 | 0.88 | KMT2A (0.47) | KMT2AMEN1ALOX5KDM4EMAPT | |
| SCHEMBL4070593 | 0.88 | HTT (0.52) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL4063193 | 0.86 | KMT2A (0.47) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL4058640 | 0.86 | HTT (0.50) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL4062714 | 0.86 | USP14 (0.52) | KMT2AMEN1ALOX5KDM4EMAPT | |
| SCHEMBL4060953 | 0.85 | MEN1 (0.61) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL4234701 | 0.85 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL4063813 | 0.85 | CLK1 (0.56) | KMT2AMEN1ALOX5KDM4EMAPT | |
| SCHEMBL4057298 | 0.83 | USP14 (0.54) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL4060871 | 0.82 | HTT (0.52) | KMT2AMEN1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |