Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016874 | 0.82 | SLC6A4 (0.57) | TAAR1KDM4ECYP3A4MAPTSLC6A4 | |
| SCHEMBL31265560 | 0.82 | SLC6A4 (0.57) | TAAR1KDM4ECYP3A4MAPTSLC6A4 | |
| SCHEMBL11268514 | 0.77 | GAA (0.46) | TAAR1IDO1KDM4EKDM1ASLC6A4 | |
| SCHEMBL2903629 | 0.77 | TAAR1 (0.59) | TAAR1IDO1KDM4ESLC6A2CYP1A2 | |
| SCHEMBL14391946 | 0.76 | SLC6A4 (0.48) | TAAR1KDM4ECYP3A4MAPTSLC6A4 | |
| SCHEMBL133921 | 0.76 | CYP2D6 (0.48) | TAAR1IDO1KDM4ECYP3A4KDM1A | |
| SCHEMBL17161254 | 0.76 | TAAR1 (0.52) | TAAR1IDO1KDM4ECYP3A4MAPT | |
| SCHEMBL11266118 | 0.76 | BCHE (0.47) | TAAR1IDO1CYP3A4KDM1ACYP1A2 | |
| SCHEMBL11161054 | 0.76 | IDO1 (0.45) | TAAR1IDO1KDM4EKDM1ACYP1A2 | |
| SCHEMBL31180009 | 0.76 | TAAR1 (0.42) | TAAR1IDO1CYP3A4KDM1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-3087091-B1 | VAR2CSA-DRUG CONJUGATES | ZYMEWORKS INC (CA) | 2021-10-20 | — | — | EP | disclosed |
| CN-110950812-B | Triazole compound and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-110950812-A | Triazole compound and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2020-04-03 | — | — | CN | disclosed |
| WO-2020063756-A1 | TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2020-04-02 | — | — | WO | disclosed |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | H. LUNDBECK A/S (DK) | 2009-07-30 | — | — | US | disclosed |
| US-7534791-B2 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2009-05-19 | — | — | US | disclosed |
| CN-101208324-A | Benzo [ b ] furan and benzo [ b ] thiophene derivatives | LUNDBECK & CO AS H (DK) | 2008-06-25 | — | — | CN | disclosed |
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | CYP1B1, TBCB, CYP4B1 | TAAR1 1517/4885IDO1 3792/4885KDM4E 1255/4885 |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | CYP1B1, TBCB, CYP4B1 | TAAR1 1517/4885IDO1 3792/4885KDM4E 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.