Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601531 | 1.00 | MAOB (0.69) | MAOBPARP10MAPTALDH1A1MAPK1 | |
| SCHEMBL9808162 | 0.92 | MAOB (0.71) | MAOBPARP10MAPTALDH1A1MAPK1 | |
| SCHEMBL1303551 | 0.89 | NPC1 (0.68) | MAOBPARP10MAPTALDH1A1RXRA | |
| SCHEMBL11603134 | 0.88 | MAOB (0.68) | MAOBPARP10MAPTALDH1A1MAPK1 | |
| SCHEMBL11601734 | 0.88 | MAOB (0.68) | MAOBPARP10MAPTALDH1A1RXRA | |
| SCHEMBL11602775 | 0.88 | MAOB (0.68) | MAOBPARP10MAPTALDH1A1RXRA | |
| SCHEMBL340618 | 0.88 | MAOB (0.67) | MAOBPARP10MAPTALDH1A1RXRA | |
| SCHEMBL11602002 | 0.88 | SMN1; SMN2 (0.61) | MAOBMAPTALDH1A1RXRARXRB | |
| SCHEMBL23084938 | 0.86 | MAOB (0.71) | MAOBPARP10MAPTALDH1A1MAPK1 | |
| SCHEMBL12353119 | 0.86 | MAOB (0.71) | MAOBPARP10MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |