Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495853 | 1.00 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL2495854 | 1.00 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL4056041 | 1.00 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL2495856 | 1.00 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL14226490 | 0.81 | — | — | |
| SCHEMBL13093838 | 0.81 | MEN1 (0.33) | — | |
| SCHEMBL13745833 | 0.80 | FNTA (0.33) | FNTAFNTB | |
| SCHEMBL5746283 | 0.80 | GRIK1 (0.41) | FNTAFNTB | |
| SCHEMBL17946581 | 0.80 | — | — | |
| SCHEMBL2759244 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112077-A1 | PROCESS FOR THE PREPARATION OF EPOTHILONE PRECURSOR COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-17 | — | — | WO | disclosed |
| EP-1874752-A1 | PROCESS FOR THE PREPARATION OF 9,10-DEHYDRO-12,13-DESOXYEPOTHILONE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2008-01-09 | — | — | EP | disclosed |
| US-7238816-B2 | Preparation of epothilone derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-20060241156-A1 | Preparation of epothilone derivatives | KOSAN BIOSCIENCES, INC. | 2006-10-26 | — | — | US | disclosed |
| WO-2006111491-A1 | PROCESS FOR THE PREPARATION OF 9,10-DEHYDRO-12,13-DESOXYEPOTHILONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241156-A1 | Preparation of epothilone derivatives | EPOR, DHPS, HCCS | FNTA 1377/4885FNTB 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.