Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961179 | 0.84 | EGFR (0.49) | EGLN1EGLN3 | |
| SCHEMBL4061386 | 0.84 | EGLN1 (0.60) | EGLN1EGLN3 | |
| SCHEMBL12777781 | 0.73 | EGLN1 (0.67) | EGLN1EGLN3 | |
| SCHEMBL8244419 | 0.73 | EGLN1 (1.00) | EGLN1EGLN3KDM4EHTT | |
| SCHEMBL3423457 | 0.72 | EGLN1 (0.63) | EGLN1EGLN3 | |
| SCHEMBL4988805 | 0.71 | EGLN1 (0.61) | EGLN1EGLN3 | |
| SCHEMBL4992247 | 0.71 | EGLN3 (0.62) | EGLN1EGLN3ALDH1A1 | |
| SCHEMBL3420724 | 0.71 | EGLN3 (0.67) | EGLN1EGLN3KDM4EHTT | |
| SCHEMBL3422298 | 0.71 | EGLN3 (0.64) | EGLN1EGLN3ALDH1A1 | |
| SCHEMBL1960754 | 0.71 | EGLN1 (0.71) | EGLN1EGLN3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039321-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | claimed |
| WO-2009039321-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | disclosed |