SCHEMBL4059170

SCHEMBL4059170

Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)NC(C)(C)C(=O)N4CCN(CCNC(=N)N)CC4)c3Cl)c2n1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4059008 0.90 BDKRB2 (1.00) BDKRB2
SCHEMBL4058976 0.89 BDKRB2 (0.81) BDKRB2
SCHEMBL4058969 0.89 BDKRB2 (0.81) BDKRB2
SCHEMBL4061298 0.88 BDKRB2 (0.81) BDKRB2
SCHEMBL4061293 0.88 BDKRB2 (0.81) BDKRB2
SCHEMBL4058723 0.88 BDKRB2 (0.81) BDKRB2
SCHEMBL4058715 0.88 BDKRB2 (0.81) BDKRB2
SCHEMBL4236027 0.87 BDKRB2 (0.75) BDKRB2
SCHEMBL4236032 0.87 BDKRB2 (0.75) BDKRB2
SCHEMBL4061599 0.85 BDKRB2 (0.81) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513531-B1 BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM MENARINI RICERCHE SPA (IT) 2009-10-21 EP claimed