Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.78 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.54 |
| ▸ | ACP1 | P24666 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059244 | 1.00 | PTPN1 (0.78) | PTPN1AKR1B1MAPTMEN1KMT2A | |
| SCHEMBL4051528 | 0.91 | PTPN1 (0.78) | PTPN1AKR1B1MAPTMEN1KMT2A | |
| SCHEMBL4051524 | 0.91 | PTPN1 (0.78) | PTPN1AKR1B1MAPTMEN1KMT2A | |
| SCHEMBL4056778 | 0.80 | PTPN1 (0.81) | PTPN1PTPN2ACP1ITGB3ITGAV | |
| SCHEMBL4056775 | 0.80 | PTPN1 (0.81) | PTPN1PTPN2ACP1ITGB3ITGAV | |
| SCHEMBL4053361 | 0.80 | PTPN1 (0.74) | PTPN1ITGB3ITGAV | |
| SCHEMBL4053358 | 0.80 | PTPN1 (0.74) | PTPN1ITGB3ITGAV | |
| SCHEMBL4057978 | 0.79 | PTPN1 (0.78) | PTPN1MAPTPTPN2ACP1ITGB3 | |
| SCHEMBL4057982 | 0.79 | PTPN1 (0.78) | PTPN1MAPTPTPN2ACP1ITGB3 | |
| SCHEMBL4056339 | 0.79 | PTPN1 (0.83) | PTPN1PTPN2ACP1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |