Methacrylic Acid

Methacrylic Acid

SCHEMBL4059537

C=C(C)C(=O)O.CC(O)CCl

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
ALDH1A1 P00352 2/20 0.55
TDP1 Q9NUW8 4/20 0.35
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TET2 Q6N021 4/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
TGFBR1 P36897 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL9779507 0.82 ALDH1A1 (0.38) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL2059838 0.82 TDP1 (0.53) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL2544208 0.82 TSHR (0.38) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL475891 0.82 TDP1 (0.53) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL5462229 0.82 TDP1 (0.53) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL2540763 0.82 ALDH1A1 (0.38) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL9779496 0.82 TSHR (0.38) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL6268592 0.82 TSHR (0.53) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL18140227 0.82 TDP1 (0.53) TSHRALDH1A1TDP1TP53TET2
Methacrylic Acid SCHEMBL4653322 0.82 TDP1 (0.53) TSHRALDH1A1TDP1TP53TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1798252-B1 CROSSLINKED FLUOROCOPOLYMER MOLDINGS UNIMATEC CO LTD (JP) 2009-10-21 EP disclosed
US-20090023863-A1 CROSS-LINKED FLUORINE-CONTAINING COPOLYMER MOLDINGS UNIMATEC CO., LTD. (JP) 2009-01-22 US disclosed
EP-1798252-A1 CROSSLINKED FLUOROCOPOLYMER MOLDINGS Unimatec Co., Ltd. (JP) 2007-06-20 EP disclosed