Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224157 | 0.86 | MAPT (0.74) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29494596 | 0.86 | MAPT (0.74) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7063538 | 0.86 | MAPT (0.74) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24913523 | 0.83 | ABCB1 (0.70) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12941004 | 0.83 | NPSR1 (0.69) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| Techtochrysin SCHEMBL249043 | 0.82 | MAPT (1.00) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| Techtochrysin SCHEMBL29494561 | 0.82 | MAPT (1.00) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28922626 | 0.81 | EGFR (0.69) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2904356 | 0.81 | MAPT (0.69) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22729259 | 0.80 | MAPT (0.81) | MAPTABCB1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110008-A1 | ANTI-ULCER ACTIVITY OF FLAVONE ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |