Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | CREB1 | P16220 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.70 |
| ▸ | RET | P07949 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224157 | 1.00 | MAPT (0.74) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7063538 | 0.92 | MAPT (0.74) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14098630 | 0.91 | BCHE (0.71) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28346184 | 0.88 | MAPT (0.71) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| Chrysin Diacetate SCHEMBL15263635 | 0.87 | KDM4E (0.78) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24913523 | 0.86 | ABCB1 (0.70) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4059660 | 0.86 | MAPT (0.70) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12941004 | 0.86 | NPSR1 (0.69) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| Chrysin SCHEMBL28551986 | 0.85 | MAPT (0.89) | MAPTABCB1CYP3A4CYP2C9CYP2C19 | |
| Techtochrysin SCHEMBL29494561 | 0.85 | MAPT (1.00) | MAPTABCB1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220105072-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES COMPLICATIONS COMPRISING NOVEL CHRYSIN DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | FRONTBIO INC (KR) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220105072-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES COMPLICATIONS COMPRISING NOVEL CHRYSIN DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | AGER, IAPP, GCG | MAPT 1884/4885ABCB1 4225/4885CYP3A4 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.