Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059747 | 0.79 | ATM (0.32) | — | |
| SCHEMBL4947044 | 0.77 | CNR1 (0.31) | RAB9ACNR1CNR2 | |
| SCHEMBL4053695 | 0.70 | RAB9A (0.40) | RAB9ACNR1CNR2ALOX15DRD2 | |
| SCHEMBL4056113 | 0.68 | SLC6A2 (0.42) | RAB9ADRD2DRD4HTR1AHTR2C | |
| SCHEMBL4943708 | 0.67 | SLC6A2 (0.43) | RAB9ADRD2DRD4HTR1AHTR2C | |
| SCHEMBL4061460 | 0.66 | SLC6A2 (0.38) | DRD2DRD4HTR1AHTR2CDRD3 | |
| SCHEMBL4053143 | 0.66 | SLC6A2 (0.42) | RAB9ADRD2HTR1AHTR2CDRD3 | |
| SCHEMBL4940915 | 0.63 | SLC6A2 (0.46) | CNR1CNR2DRD2HTR3ADRD3 | |
| SCHEMBL5791704 | 0.62 | KMT2A (0.51) | RAB9AHTR3A | |
| SCHEMBL14631807 | 0.62 | RAB9A (0.41) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |