Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473371 | 1.00 | CCNC (0.57) | CCNCCDK8KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL6954216 | 0.98 | CCNC (0.56) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL29852290 | 0.86 | KMT2A (0.56) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL1973790 | 0.86 | KMT2A (0.56) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL31411163 | 0.85 | ACHE (0.47) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL27660501 | 0.84 | KMT2A (0.51) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL6604392 | 0.83 | KMT2A (0.60) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL29852314 | 0.83 | KMT2A (0.60) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL27453198 | 0.83 | CCNC (0.55) | CCNCCDK8KMT2AMAPTLMNA | |
| SCHEMBL27454851 | 0.83 | CCNC (0.48) | CCNCCDK8KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108239089-A | A kind of synthetic method of AVM hereinafter Batan sodium | 浙江医药股份有限公司新昌制药厂 | 2018-07-03 | — | — | CN | claimed |
| CN-1856477-A | Isoquinoline potassium channel inhibitors | MERCK & CO INC (US) | 2006-11-01 | — | — | CN | claimed |
| EP-4658667-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | Merck Sharp & Dohme LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163691-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | MERCK SHARP & DOHME LLC (US) | 2024-08-08 | — | — | WO | disclosed |
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| US-11770971-B2 | Esters containing aromatic groups as solvents for organic electronic formulations | MERCK PATENT GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
| US-11770971-B2 | Esters containing aromatic groups as solvents for organic electronic formulations | MERCK PATENT GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
| CN-114316187-B | Low-density low-smoke-toxicity high-flame-retardance polyurethane rigid foam and preparation method thereof | 万华化学（烟台）容威聚氨酯有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-114787359-A | Method for producing peptide containing unnatural amino acid | 中外制药株式会社 | 2022-07-22 | — | — | CN | disclosed |
| EP-3391428-B1 | ESTERS CONTAINING AROMATIC GROUPS AS SOLVENTS FOR ORGANIC ELECTRONIC FORMULATIONS | MERCK PATENT GMBH (DE) | 2022-06-29 | — | — | EP | disclosed |
| CN-114316187-A | Low-density low-smoke-toxicity high-flame-retardance polyurethane rigid foam and preparation method thereof | 万华化学（烟台）容威聚氨酯有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-1248256-A | Process for preparation of 4H-4-oxo-quinolizine-3-carboxylic acid derivatives | ABBOTT LAB (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | disclosed |
| CN-1130898-A | Difluorostone antiviral analogs | MERRELL DOW PHARMA (US) | 1996-09-11 | — | — | CN | disclosed |
| CN-1030451-C | Process for preparing benzothiazole derivatives | EISAI CO LTD (JP) | 1995-12-06 | — | — | CN | disclosed |
| CN-1112104-A | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-22 | — | — | CN | disclosed |
| CN-1075480-A | New aryl carbonylamino alkyl-dihydro-oxo pyridine compounds and production thereof and application | HOECHST AG (US) | 1993-08-25 | — | — | CN | disclosed |
| CN-1065457-A | Benzothiazole derivant | EISAI CO LTD (JP) | 1992-10-21 | — | — | CN | disclosed |
| CN-1043125-A | Be used as the aryl urea of the replacement of high-potency sweetener | NUTRASWEET CO (US) | 1990-06-20 | — | — | CN | disclosed |
| CN-86104284-A | Be used for the treatment of 1 of cardiovascular disorder, the preparation method of 4-dihydrogen pyridine derivative | — | 1987-04-01 | — | — | CN | disclosed |