SCHEMBL4060066

SCHEMBL4060066

O=CCc1ccnc(Br)c1F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4050304 0.78 TRIM24 (0.36) TRIM24TRIM33
SCHEMBL26613699 0.76
SCHEMBL4668403 0.75
SCHEMBL20607540 0.75 KDM4E (0.39)
SCHEMBL30900913 0.75
SCHEMBL30558703 0.73 TRIM24 (0.52) TRIM24TRIM33
SCHEMBL1157182 0.73 TRIM24 (0.52) TRIM24TRIM33
Bromide SCHEMBL2724195 0.72 TRIM24 (0.50) TRIM24TRIM33
SCHEMBL17512179 0.71 TRIM24 (0.53) TRIM24TRIM33
SCHEMBL18953972 0.71 KDM1A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009114552-A1 HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2009-09-17 WO disclosed