Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157182 | 1.00 | TRIM24 (0.52) | TRIM24TRIM33CYP11B1CYP11B2PARP1 | |
| Bromide SCHEMBL2724195 | 0.98 | TRIM24 (0.50) | TRIM24TRIM33CYP11B1CYP11B2PARP1 | |
| SCHEMBL29164411 | 0.80 | CYP11B1 (0.45) | TRIM24TRIM33CYP11B1CYP11B2PARP1 | |
| SCHEMBL11744380 | 0.79 | ALDH1A1 (0.38) | TRIM24TRIM33KDM4ECYP1A2MAPT | |
| SCHEMBL31288450 | 0.77 | — | — | |
| SCHEMBL9383289 | 0.77 | — | — | |
| SCHEMBL1811013 | 0.76 | NAPRT (0.41) | TRIM24TRIM33KDM4ECYP1A2MAPT | |
| SCHEMBL1645573 | 0.76 | P2RX7 (0.41) | TRIM24TRIM33KDM4ECYP1A2MAPT | |
| SCHEMBL21054513 | 0.76 | BACE1 (0.42) | TRIM24TRIM33KDM4ECYP1A2MAPT | |
| SCHEMBL12481228 | 0.76 | KDM4E (0.38) | TRIM24TRIM33KDM4ECYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051360-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2025-02-13 | — | — | US | disclosed |
| CN-114075221-B | Substituted heteroaryl compounds, compositions and uses thereof | 广东东阳光药业股份有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-116332961-A | Substituted heteroaryl compounds, compositions and uses thereof | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051360-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF | TYK2, JAK2, JAK1 | TRIM24 1875/4885TRIM33 996/4885CYP11B1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.