Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218377 | 0.81 | STAT3 (0.49) | ALDH1A1SMN1; SMN2STAT3BRCA1CYP1A2 | |
| SCHEMBL8205691 | 0.79 | PLA2G10 (0.46) | ALDH1A1SMN1; SMN2PLA2G10PLA2G2ACYP1A2 | |
| SCHEMBL11215817 | 0.75 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2STAT3BRCA1POLB | |
| SCHEMBL1395763 | 0.75 | POLB (0.55) | ALDH1A1SMN1; SMN2CYP1A2L3MBTL1POLB | |
| SCHEMBL13162542 | 0.74 | HSD17B10 (0.59) | ALDH1A1SMN1; SMN2STAT3BRCA1POLB | |
| SCHEMBL7823640 | 0.74 | CYP1A2 (0.73) | ALDH1A1SMN1; SMN2STAT3CYP1A2POLB | |
| SCHEMBL11521564 | 0.73 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2STAT3BRCA1L3MBTL1 | |
| SCHEMBL24612455 | 0.73 | HTR2A (0.42) | SMN1; SMN2L3MBTL1HTR2APOLBKMT2A | |
| SCHEMBL5794957 | 0.73 | HTR2A (0.52) | SMN1; SMN2PLA2G10PLA2G2AL3MBTL1PTPN1 | |
| SCHEMBL6459722 | 0.72 | HTR2A (0.43) | SMN1; SMN2PLA2G10PLA2G2AHTR2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553646-B2 | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-06-30 | — | — | US | disclosed |
| WO-2007027328-A2 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070026507-A1 | MICROBIAL SULFOXIDATION AND AMIDATION OF BENZHDRYLSULFANYL CARBOXYLIC ACIDS AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-02-01 | — | — | US | disclosed |