Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | PRKD1 | Q15139 | 6/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 6/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371310 | 0.85 | SORD (0.58) | HRH3PRKD1PRKD2PRKD3PRKCA | |
| SCHEMBL31468673 | 0.84 | CXCR4 (0.49) | HRH3PRKD1PRKD2PRKD3HRH4 | |
| SCHEMBL14331816 | 0.82 | HRH3 (0.54) | HRH3PRKD1PRKD2PRKD3PRKCA | |
| SCHEMBL31706338 | 0.81 | HRH3 (0.52) | HRH3PRKD1PRKD2PRKCAPRKCQ | |
| SCHEMBL31706298 | 0.81 | HRH3 (0.52) | HRH3PRKD1PRKD2PRKCAPRKCQ | |
| SCHEMBL4197090 | 0.78 | HRH3 (0.46) | HRH3HRH4 | |
| SCHEMBL8966785 | 0.78 | PRKCQ (0.71) | HRH3PRKCAPRKCQPRKCD | |
| SCHEMBL4350540 | 0.76 | HRH3 (0.48) | HRH3HRH4KDM4E | |
| SCHEMBL27786169 | 0.76 | PRKD1 (0.66) | HRH3PRKD1PRKD2PRKD3PLD1 | |
| SCHEMBL23458788 | 0.76 | HRH3 (0.65) | HRH3PRKCAPRKCQPRKCDHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079756-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | Cara Therapeutics, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008060552-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | CARA THERAPEUTICS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |