SCHEMBL4060310

SCHEMBL4060310

Oc1nc2ccccc2c(O)c1O.[Nd]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 3/20 0.43
GLA P06280 3/20 0.43
MAOA P21397 2/20 0.43
HPGD P15428 2/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CHRM2 P08172 1/20 0.43
ADRA2A P08913 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CHRM1 P11229 1/20 0.43
NQO2 P16083 1/20 0.43
DRD1 P21728 1/20 0.43
ACHE P22303 1/20 0.43
SLC6A2 P23975 1/20 0.43
ADRA1A P35348 1/20 0.43
OPRM1 P35372 1/20 0.43
KCNH2 Q12809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311283 0.98 KDM4E (0.44) KDM4EALDH1A1GLAMAOAHPGD
SCHEMBL851828 0.98 KDM4E (0.44) KDM4EALDH1A1GLAMAOAHPGD
SCHEMBL27797272 0.95 KDM4E (0.43) KDM4EALDH1A1GLAMAOAHPGD
Acridone SCHEMBL243819 0.80 KDM4E (0.56) KDM4EALDH1A1GLAMAOAHPGD
SCHEMBL4278260 0.78 ERN1 (0.47) KDM4EALDH1A1GLAMAOAHPGD
Acridone SCHEMBL429571 0.78 ALDH1A1 (0.54) KDM4EALDH1A1GLAMAOAHPGD
Acridone SCHEMBL10800711 0.78 KDM4E (0.54) KDM4EALDH1A1GLAMAOAHPGD
Acridone SCHEMBL5719993 0.78 KDM4E (0.54) KDM4EALDH1A1GLAMAOAHPGD
Acridone SCHEMBL345058 0.78 ALDH1A1 (0.54) KDM4EALDH1A1GLAMAOAHPGD
Acridone SCHEMBL27574706 0.78 KDM4E (0.54) KDM4EALDH1A1GLAMAOAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7589329-B1 Systems and methods for remote optical sensing HONEYWELL INTERNATIONAL INC. (US) 2009-09-15 US disclosed